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Purpose
In vivo magnetic resonance spectroscopy (MRS) is the only technique capable of non‐invasively assessing metabolite concentrations in the brain. The lack of alternative methods makes validation of MRS measures challenging. The aim of this study is to assess the validity of MRS measures of human brain metabolite concentrations by comparing multiple MRS measures acquired using different MRS...
Purpose
To combine the metabolite‐cycling technique with diffusion‐weighted 1H‐MR spectroscopy and to use the inherent water reference for compensation of motion‐related signal loss for improved estimation of metabolite apparent diffusion coefficients (ADCs).
Methods
Diffusion‐weighted spectra of water and metabolites were acquired simultaneously using metabolite‐cycling at 3 T. The water information...
In this paper, a novel spectrum separation technique based on sparse representation is proposed to deal with Magnetic Resonance Spectroscopy (MRS) quantification which is used to measure the levels of different metabolites in brain tissues. Since a measured MR spectrum contains the spectra of numbers of metabolites and a baseline, the separation and quantification of them becomes difficult. A nonnegative...
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