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We investigated the effects of the carotid sinus baroreflex on coupling of the left ventricle (LV) and the arterial system in twelve anesthetized dogs, with all nerves and carotid sinus circulation intact and instrumented to measure LV pressure and volume. The Rheosreg device was used to directly electrically stimulate the carotid sinus baroreceptors. Stimulation resulted in a significant reduction...
The aim of this study was to evaluate whether detection performance of ACC/ESC STEMI criteria based on 12-lead ECG can be improved by using criteria from 3 vessel-specific leads (VSLs) derived from reduced lead sets of 12-lead ECG using 3 limb electrodes at Masson-Likar torso sites and 2 chest electrodes at precordial sites V1 to V6. There are a total of 15 such lead sets and each can be recorded...
Ventricular tachycardia and ventricular fibrillation are known to be two types of cardiac arrhythmias that usually take place during acute ischemia and frequently lead to sudden death. In this work, we have studied the different patterns of activation displayed in a virtual ventricular slab preparation after premature stimulation during acute ischemia. Furthermore, we also have analyzed the vulnerable...
It is well known that ventricular fibrillation (VF) is a major cause of sudden cardiac death in developed countries. Myocardial regional acute ischemia constitutes a heterogeneous substrate which tends to destabilize the electrical depolarizing wave front, thus favouring VF. Functional re-entry in the transmural wall has been hypothesized as the underlying mechanism of VF. In this work, we have theoretically...
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