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Peptides in human body fluids closely mirror processes of protein synthesis, processing and degradation. Since peptide levels and composition in the circulation fluctuate in close correlation with specific condition (either physiological or pathological) of an individual, comprehensive peptide analysis may unravel novel disease biomarkers or pave the way to new diagnostic approaches. Discovery of...
Proteins are major components that directly determine phenotypes of cells and organisms, in either normal or pathological conditions. Because of numerous post-translational events that modify structure and function of proteins, the knowledge of genomes is only at the beginning of understanding of the full complexity of biological systems. 'Proteomics' is the study of proteomes, which addresses proteins'...
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