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Physiological models have been proposed to describe the processes that underlie the link between neural and hemodynamic activity in the brain. Among these, the Balloon model describes the changes in blood flow, blood volume and oxygen concentration when an hemodynamic response is ensuing neural activation. Next, an hemodynamic model links these variables to the blood-oxygen-level-dependent (BOLD)...
Derived from the pioneer ionic Hodgkin-Huxley model and due to its simplicity and richness from a point view of nonlinear dynamics, the FitzHugh-Nagumo model (FHN) is one of the most successful simplified neuron / cardiac cell model. There exist many variations of the original FHN model. Though these FHN type models help to enrich the dynamics of the FHN model, the parameters used in these models...
As a well-known property of the heart, many studies has reported that the left ventricular end-systolic pressure-volume relationship (ESPVR) is linear. However, the reason of the linearity is poorly understood. This article presents a multiscale circulation model to be a tool for theoretical analyses on the mechanism of the linearity of ESPVR. The model is composed of three sub-models; a detailed...
This study addresses the question which factors are responsible for reported positive correlations between solar induced fluorescence (SIF) and gross primary production (GPP). A sensitivity analysis of the model SCOPE, which simulates photosynthesis, fluorescence emission and radiative transfer in canopies, has been carried out for four different plant functional types (PFT): tropical rainforest,...
The fine architecture of sleep-wake behavior shows a distinct dynamic structure with distributions of rat sleep and wake bout durations displaying qualitatively different profiles. Wake bout durations follow a power-law relation whereas sleep bout durations are exponentially distributed. We show that a physiologically-based sleep-wake regulatory network model with an underlying deterministic structure...
From a historical perspective, we are at a stage in science comparable to the post-Newtonian developments of physics, engineering and technology-with the key difference that now we are trying to create a solid quantitative mathematical basis for biology, physiology and the study of disease. The enormous complexity of living systems means that understanding their behaviour in a quantitative mathematical...
In order to coordinate with and promote the scientific process of the national fencing team, we developed the decision support system for training. In fencing training, we established a two-way reasoning model based on Bayesian network and found the relationship between training process and physiological indicators. Combined with experienced knowledge and sample data, we did research on knowledge...
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