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Studies were conducted to establish the biochemical and pharmacological effects of W-2721 after irradiation in the mouse tests for up to 30 days of irradiation. Adult mice were irradiated with 3, 6, and 8 Gy of /sup 60/Co gamma rays with and without pretreatment by WR-2721 at a dose rate of 400 mg/kg body weight. Animals were sacrificed at different postirradiation days to estimate the amount of DNA,...
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