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Computational fluid dynamics (CFD) simulations of blood flow within intracranial aneurysms may provide important hemodynamic information for treatment planning. However, reliable validation is required prior to applications in clinical environments. For that purpose, we introduce a workflow for generating virtual digital subtraction angiographies (DSA) based on CFD results and real patient-individual...
The amplitude of the BOLD signal depends heavily upon the resting blood volume fraction (V0). However, most existing haemodynamic data assimilation studies pretermit such concern through assigning arbitrarily the value in a physiological plausible range. In this work, we presented the first exploration of the influence of the fraction V0 to model estimation, where the exact value of V0 was calibrated...
Hemodynamics play an important role in the pathogenesis of intracranial aneurysms and are believed to provide valuable information to predict aneurysmal rupture. Using image-based vascular models and computational fluid dynamics (CFD) techniques, the inter-aneurysmal hemodynamics can be studied in depth. In this paper, the effect of using different image-modalities is evaluated by investigating 4...
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