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Quantitative analysis of the myocardial interstitial space is gaining increased interest as a biomarker in the MRI and clinical cardiovascular communities. To investigate the effect of water exchange on the calculation of myocardial extracellular volume (ECV), we employed two tissue models: the standard ECV two‐point model (SM) and the shutter speed model (SSM). Twenty individuals (18 men and two...
This paper offers a critical review of the properties, methods and potential clinical application of sodium (23Na) MRI in human heart. Because the tissue sodium concentration (TSC) in heart is about ~40 µmol/g wet weight, and the 23Na gyromagnetic ratio and sensitivity are respectively about one‐quarter and one‐11th of that of hydrogen (1H), the signal‐to‐noise ratio of 23Na MRI in the heart is about...
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