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Arterial wave speed estimated invasively from pressure (P) and velocity (U) measurements using the P-U loop method, or non-invasively from diameter (D) and U measurements using the lnD-U loop method, assume that during early systole 1) backward-running waves are absent and 2) wave speed is constant. These assumptions also form the basis of a method for correcting time lags between P (or lnD) and U...
With ultrasound strain imaging, the function of tissue and organs can be identified. The technique uses multiple images, acquired from tissue under different degrees of deformation. We developed techniques for cardiovascular applications. The displacement of tissue can be determined at micrometer scale using the raw (i.e., radio frequency, RF-) ultrasound data, containing the amplitude as well as...
An important goal in clinical cardiology is the non-invasive quantification of regional cardiac deformation. While many methods have been proposed for the estimation of 3D left ventricular deformation and strains derived from 4D ultrasound, currently there is a lack of in vivo clinical validation of these algorithms on humans. In this paper, we describe the experiments used in validating cardiac deformation...
Ultrasound strain imaging has been proposed to quantitatively assess myocardial contractility. Cross-correlation- based 2-D speckle tracking (ST) and auto-correlation-based tissue Doppler imaging (TDI) [often called Doppler tissue imaging (DTI)] are competitive ultrasound techniques for this application. Compared with 2-D ST, TDI, as a 1-D method, is sensitive to beam angle and suffers from low strain...
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