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Aging is associated with a gradual decline in circulating testosterone concentrations and decreased musculature in men. While testosterone administration is often considered when symptoms of hypogonadism are presented, the long-term effects of androgen use on muscle physiology are not yet fully understood.The definition of hypogonadism in men remains obscure but is generally indicated by total testosterone...
To determine whether insulin sensitizers lower androgen levels and whether androgen suppression improves insulin resistance in nondiabetic postmenopausal women.Randomized, double-blind, placebo-controlled study.Clinical and Translational Research Center of a university hospital.Thirty-five postmenopausal women aged 50–79 years with insulin resistance and higher T levels.Subjects were randomized to...
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