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The ‘default mode network’ (DMN), a collection of brain regions including the posterior cingulate cortex (PCC), shows reliable inter-regional functional connectivity at rest. It has been implicated in rumination and other negative affective states, but its role in suicidal ideation is not well understood. We employed seed based functional connectivity methods to analyze resting state fMRI data in...
We propose statistical inference based on the Least Absolute Shrinkage and Selective Operator (Lasso) regression as a framework to investigate the relationship between structural brain connectivity data (DTI) and functional connectivity data (fMRI). Regions of interest (ROIs) are obtained from an accurate atlas-based segmentation. We use direct structural connections to model indirect (higher-order)...
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