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Chitosan microparticles (CMs) were prepared with tripolyphosphate by spray-drying. Effects of polymer molecular weight, sonication power, cross-linking time and concentration of TPP on release profiles of catalytic or third domain pseudomonas exotoxin A (PEIII) and morphology of CMs were evaluated. The mean particle sizes of CMs were in the range from 1.09–1.46μm and antigen loading efficiencies were...
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