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Summary In about 80 % of fetuses with trisomies 21, 18 or 13 and Turner syndrome there is an increased collection of fluid in the neck region that can be visualized sonographically at 10–14 weeks gestation as increased nuchal translucency thickness. The pathophysiology of this common phenotypic expression of different chromosomal abnormalities is uncertain, but there is some evidence that the underlying...
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