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Background. There are few updated data on rates of hospital mortality of diabetic patients and length of their hospital stay on a country level. To determine such rates we provided analysis using claims data from a Nationwide General Hospital Morbidity Study carried out by the National Institute of Public Health – National Institute of Hygiene (NIPHNIH) in Warsaw from 2010 to 2018. Objective. The...
Background. Many scientific reports have shown a decrease in total cerebrovascular disease (CeVD) mortality over the past few decades, but too little attention has been paid to premature mortality. CeVD accounted for 22.5% and 17.8% of premature cardiovascular disease deaths in Poland, in 2000 and 2016, respectively. Objective. The aim of the study was to analyse premature CeVD mortality in the Polish...
Background. Following pharmacological recommendations and leading a healthy lifestyle are imperative to improve the health and quality of life of patients with heart failure (HF). Material and methods. This cross-sectional, observational study examined 100 patients with HF who were treated in the cardiology department. The average age of the respondents was 70±14 years (mean±SD), and the majority...
Background. The interrelation between omeprazole use and the possibility of developing nosocomial pneumonia, acute kidney damage and Clostridium difficile-induced diarrhea in patients with sepsis requires further study. Material and methods. 200 patients with severe craniocerebral injury that underwent surgery for the pathology and developed sepsis in the postoperative period were examined in a blind,...
Background. The aim of this study was to investigate the influence of selected factors such as place of residence, education, age, duration of hospitalization and pain intensity before and after hip replacement surgery on the level of acceptance of the illness, on the subjective assessment of the patient’s state of health during surgery and on the level of pain and the ability to manage and reduce...
Background. A tendency to venous thromboembolism is otherwise called hypercoagulability or thrombophilia. This disease can be acquired or have a genetic background, and may lead to pulmonary embolism. The basis for analysis and selection of treatment is genetic diagnosis, which detects the G1691A mutation in the factor V gene (factor V Leiden) – the best known congenital thrombophilia marker. Material...
Background. Acute ascending thrombophlebitis of the great saphenous vein (GSV) is an adverse complication of varicose veins of the lower extremities. Conventional surgical treatment comprises traumatic removal of thrombotic vein trunk by means of a Babcock probe. Endovascular welding is a promising, minimally invasive treatment for varicose veins, which may also be applied for hemodynamic correction...
Background. The aim of this work was to examine the awareness of patients with diabetes mellitus (DM) on the importance of physical activity (PA) in the prevention and treatment of their disease. Material and methods. The survey was completed by 178 respondents (47.3% women, 52.7% men), of whom 69.1% were dependent on exogenous insulin. Data was collected in April 2019 via a questionnaire given to...
Recent clinical and experimental studies indicate that multiple sclerosis (MS) develops as consequence of a failed interplay between genetic and environmental factors. An ever‑growing number of risk genes have been recognised that support an autoimmune response against the body’s own brain matter. Together, these increase susceptibility to MS without actually triggering the disease. Recent experimental...
Given the urgent need for a disease modifying treatment of Alzheimer’s disease (AD), there is increasing interest in tau‑based therapeutics. In a comparative study, methylthioninium chloride (MTC) and leucomethylthioninium salts (LMTX®) (5‑75 mg/kg; oral administration for 3-8 weeks) were assessed preclinically in two novel transgenic tau mouse lines (Line 1, Line 66). Behavioural and histopathological...
Basic research into neurodegenerative disorders, like Alzheimer’s disease, is heavily focused on understanding genetic susceptibility and biochemical triggers of pathology, as well as disturbances to the intrinsic electrophysiological properties of affected neurons. Often overlooked is the role of mechanics, particularly mechanical properties and mechano‑sensitivity/‑responsiveness of neurons and...
Glial pathology and energy metabolism changes in the brain precede symptoms of Parkinson’s disease (PD) and multiple other neurodegenerative diseases. Astrocytes govern and regulate a large part of the energy metabolism in the brain. Prolonged impairment of astrocytic functions could increase the vulnerability of dopaminergic neurons in the substantia nigra (SN). In this model, 40‑50% of dopaminergic...
Background. Breast cancer (BC) is the most common malignant cancer among women in Poland. As we do not have sufficient knowledge about origin of this disease, women’s awareness and attitudes concerning the few well-known BC risk factors play a key role in the prevention and early detection of BC. Material and methods. The questionnaire was answered by 380 women, 45 years and older, in Poland between...
Background. Children with intellectual disability need special help from their parents, proportional to the type and degree of their disability. They require individual treatment, and their development depends not only on their health status but also on environmental conditions, measures and actions taken by supporting institutions, and social attitudes. Most often, mothers engage in a child care...
Background. Chronic back pain is one of the most common causes of disability. It is a civilisation disease and up to 75% of women over the age of 55 suffer from it. The aim of this study was to assess the degree of disability and limitations in the daily functioning of women with lumbar spine pain depending on socio-demographic factors. Material and methods. The study included a group of 274 professionally...
Background. Diabetes, due to its prevalence and the rapid increase in the number of new incidences, has been recognized as an epidemic of the 21st century. It is estimated that over 3 million people in Poland currently suffer from this disease. According to the Ministry of Health, the knowledge of the society about diabetes is too little and insufficient. The aim of the study was to investigate and...
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