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The use of quantitative imaging for the characterization of hepatic tumors in magnetic resonance imaging (MRI) can improve the diagnosis and therefore the treatment of these life-threatening tumors. However, image parameters remain difficult to interpret because they result from a mixture of complex processes related to pathophysiology and to acquisition. These processes occur at variable spatial...
A multiscale model of blood clot (thrombus) formation is extended by adding a sub-model of the tissue factor (TF) pathway of blood coagulation to provide more biologically relevant description of coagulation process. A combination of experimental approach, image analysis and a multiscale modeling is used for studying role of factor VII and fibrin in limiting growth of a blood clot. The simulations...
The use of quantitative imaging for the characterization of hepatic tumors in MRI can improve the diagnosis and therefore the treatment. However, image parameters remain difficult to interpret because they result from a mixture of complex processes related to pathophysiology and to acquisition. In particular, the lesion arterialization is prominent in the resulting contrast between normal and tumoral...
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