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Maternal high‐fat diet (HFD) is linked to obesity and inflammation, predisposing offspring to metabolic and nutritional disorders. Accordingly, elevated blood levels of lipopolysaccharide (LPS) are also related to inflammation and metabolic complications in the offspring. The aim of this study was to evaluate the effects of the association of maternal HFD (gestation and lactation) and the LPS injection...
IL‐20 is a proinflammatory cytokine of the IL‐10 family and involved in several diseases. However, the regulatory role of IL‐20 in obesity is not well understood. We explored the function of IL‐20 in the pathogenesis of obesity‐induced insulin resistance by ELISA, Western blotting and flow cytometry. The therapeutic potential of IL‐20 monoclonal antibody 7E for ameliorating diet‐induced obesity was...