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article

Charakterystyka osuwisk powstałych na hałdach po górnictwie rud żelaza w rejonie częstochowskim

Konrad Górka, Andrzej Piotrowski

Przegląd Geologiczny > 2022 > Vol. 70, nr 9 > 682--694

For about 600 years Middle Jurassic iron ores had been mined in the Częstochowa region. This process created many forms, among which mining and processing waste dumps are the best visible in this area. After the mining process had stopped, mass movements occured in the surface of the dumps. The paper presents specificity of landslides developed in dumps in the Częstochowa region, intensity of this...

article

Multivariate decoding methods reveal how speaking two dialects affects executive functions

Yan Jing Wu, Qinpu Dang, Zhaoqi Zhang, Haoyun Zhang, more

European Journal of Neuroscience > 57 > 5 > 840 - 853

How speaking two languages affects executive functions has been a long‐standing debate and the mechanisms underlying the observed cognitive advantages of bilingualism remain unspecified. Here, using multivariate pattern classification methods, we decoded spatial patterns of neural signals associated with Flanker task performance in mono‐dialectal and bi‐dialectal speakers of Chinese. While univariate...

article

Auditory spatial attention gradients and cognitive control as a function of vigilance

Edward J. Golob, Jeremy T. Nelson, Jaelle Scheuerman, Kristen B. Venable, more

Psychophysiology > 58 > 10 > n/a - n/a

Selection and effort are central to attention, yet it is unclear whether they draw on a common pool of cognitive resources, and if so, whether there are differences for early versus later stages of cognitive processing. This study assessed effort by quantifying the vigilance decrement, and spatial processing at early and later stages as a function of time‐on‐task. Participants performed an auditory...

article

A strategy to characterize chlorophyll protein interaction in LIL3

Astrid Elisabeth Mork-Jansson, Lutz Andreas Eichacker

Plant Methods > 2019 > 15 > 1 > 1-13

Background The function of proteins is at large determined by cofactors selectively bound to protein structure. Without chlorophyll specifically bound to protein, light harvesting and photosynthesis would not be possible. The binding of chlorophyll to light harvesting proteins has been extensively studied in reconstitution assays using proteins expressed in vitro; however, the mechanism of the reconstitution...

article

Single-trial dynamics explain magnitude sensitive decision making

Angelo Pirrone, Wen Wen, Sheng Li

BMC Neuroscience > 2018 > 19 > 1 > 1-10

Background Previous research has reported or predicted, on the basis of theoretical and computational work, magnitude sensitive reaction times. Magnitude sensitivity can arise (1) as a function of single-trial dynamics and/or (2) as recent computational work has suggested, while single-trial dynamics may be magnitude insensitive, magnitude sensitivity could arise as a function of overall reward received...

article

Solving electromagnetic scattering from complex composite objects with domain decomposition method based on hybrid surface integral equations

Ran Zhao, Zhi Xiang Huang, Yongpin P. Chen, Jun Hu

Engineering Analysis with Boundary Elements > 2017 > 85 > C > 99-104

A new domain decomposition method (DDM) is proposed to solve the electromagnetic scattering from microstrip antennas and arrays conformally mounted on a perfect electrically conducting (PEC) platform. Based on the local geometrical structures and material properties, the complex composite structures is first decomposed into independent sub-domains, following the philosophy of divide and conquer. The...

article

Pharmacokinetic Characterization and Dose Selection of a Novel Sumatriptan Nasal Spray Formulation, DFN‐02

Arindam Pal, Anirudh Gautam, Sagar Munjal

The Journal of Clinical Pharmacology > 57 > 11 > 1472 - 1478

This 3‐way, single‐dose, randomized crossover study evaluated the pharmacokinetics (PK) and dose proportionality of 5‐, 10‐, and 15‐mg doses of intranasal sumatriptan (DFN‐02) coformulated with a permeation enhancer (DDM) in 18 healthy adults. The objective was to determine which DFN‐02 dose approximates the PK of a 6‐mg dose of sumatriptan delivered via subcutaneous injection in the deltoid muscle...

chapter

Feature-based diagnostic distortion measure for unsupervised self-guided biomedical signal compressors

Jose Santos, Dongming Peng, Michael Hempel, Hamid Sharif

2017 IEEE 13th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob) > 1 - 8

2017 IEEE 13th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob)

In this work, the advantages of coupling biomedical signal compressors with clinical feature-based distortion measures are demonstrated. Such a coupling allow biomedical signal compressors to self-establish hard limits with regards to choices surrounding compression ratios, or ‘quality settings’, a compressor can safely choose from to guarantee that features of clinical significance are protected...

article

DDM at Work

Chunshan Xu, Junying Liang, Haitao Liu

Physics of Life Reviews > 2017 > 21 > C > 233-240

We provide responses to the commentaries in this volume to evaluate, clarify and extend some of the arguments in Dependency distance: A new perspective on syntactic patterns in natural languages. Evidences show that DDM (dependency distance minimization) is an important linguistic universal, biologically or cognitively motivated, in shaping the language system. As a general tendency, DDM works quite...

article

Estimation of maximum power point of a double diode model photovoltaic module

Himanshu Sekhar Sahu, Sisir Kumar Nayak

IET Power Electronics > 2017 > 10 > 6 > 667 - 675

This study presents a robust technique to estimate the maximum power point (MPP) of a double-diode model (DDM) photovoltaic (PV) module. The MPP of the DDM PV module under different environmental conditions (DECs) are estimated by using the simple and computationally efficient Levenberg–Marquardt method. The variation of double diode PV module parameters with the change of temperature and irradiation...

article

A multicenter, open-label, long-term safety and tolerability study of DFN-02, an intranasal spray of sumatriptan 10 mg plus permeation enhancer DDM, for the acute treatment of episodic migraine

Sagar Munjal, Elimor Brand-Schieber, Kent Allenby, Egilius L.H. Spierings, more

The Journal of Headache and Pain > 2017 > 18 > 1 > 1-8

Background DFN-02 is a novel intranasal spray formulation composed of sumatriptan 10 mg and a permeation-enhancing excipient comprised of 0.2% 1-O-n-Dodecyl-β-D-Maltopyranoside (DDM). This composition of DFN-02 allows sumatriptan to be rapidly absorbed into the systemic circulation and exhibit pharmacokinetics comparable to subcutaneously administered sumatriptan. Rapid rate of absorption is suggested...

chapter

Investigation of efficient simulation methods for finite large X-band arrays in HFSS

Elicia Harper, Carolyn Reistad, Alkim Akyurtlu

2017 International Applied Computational Electromagnetics Society Symposium - Italy (ACES) > 1 - 2

2017 International Applied Computational Electromagnetics Society Symposium - Italy (ACES)

This paper investigates different simulation methods in HFSS for periodic arrays. Due to extensive computation times and memory requirements of explicitly simulating a large finite array, both HFSS's finite array domain decomposition method (DDM) and an infinite array simulation are studied as alternatives to reduce total simulation time. For these tests, a helix antenna operating between 8GHz and...

article

Rapid and sensitive analysis of N-glycans by MALDI-MS using permanent charge derivatization and methylamidation

Wenjie Gao, Henghui Li, Yanyan Liu, Yuhong Liu, more

Talanta > 2016 > 161 > C > 554-559

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has become an important technology for glycan analysis due to its ease of operation, short analysis time and impurity tolerance. However, the low ionization efficiency of N-glycans led to the difficulty in analyzing glycans of low abundance in complex biological samples due to the lack of basic site for protonation. Therefore,...

article

Integrated simulation of multi-stage hydraulic fracturing in unconventional reservoirs

Huiying Tang, Philip H. Winterfeld, Yu-Shu Wu, Zhao-qin Huang, more

Journal of Natural Gas Science and Engineering > 2016 > 36 > PA > 875-892

In recent years, the multi-stage hydraulic fracturing technology has been widely applied to unconventional reservoirs. In order to optimize the stimulation performance and achieve economic production rates, the underlying physics and the impacts of different designing parameters must be quantitatively understood prior to the operations. Although many numerical models have been developed for this purpose,...

article

A Randomized Trial Comparing the Pharmacokinetics, Safety, and Tolerability of DFN‐02, an Intranasal Sumatriptan Spray Containing a Permeation Enhancer, With Intranasal and Subcutaneous Sumatriptan in Healthy Adults

Sagar Munjal, Anirudh Gautam, Elliot Offman, Elimor Brand‐Schieber, more

Headache: The Journal of Head and Face Pain > 56 > 9 > 1455 - 1465

Objective/Background Intranasal sumatriptan (Imitrex^®) may be an alternative for patients who refuse injections and cannot tolerate oral agents, but due to low bioavailability and slow absorption, the clinical utility of the currently marketed formulation is limited, highlighting an unmet need for an effective non‐oral migraine medication with a rapid onset of action. To overcome the slow absorption...

article

Coupling of BEM subdomains – BETI applied to collocation BEM with mixed basis functions

Bernhard Lindner, Christian Duenser, Gernot Beer

Engineering Analysis with Boundary Elements > 2016 > 71 > C > 79-91

This work is about the coupling of subdomains for elasticity problems using the boundary element tearing and interconnecting method (BETI). BETI is a substructuring technique which is able to solve large problems involving subdomains efficiently, because its formulation is ideally suited for parallel computation. In contrast to the original formulation of BETI, where the symmetric Galerkin boundary...

chapter

Influences of 3D Aircraft Model to ILS Localizer

Junichi Honda, Hisashi Yokoyama, Hirohisa Tajima, Takuya Otsuyama

2016 10th International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS) > 180 - 185

2016 10th International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS)

This paper is concerned with a numerical simulation of ILS subsystem Localizer (LOC) which provides the guidance in the horizontal position of an aircraft for the runway center line. The LOC emits two types of signals, that is, carrier wave and sideband waves modulated by a 90 Hz and a 150 Hz tone. The performance of the LOC is given by the difference in the depth of the modulation (DDM). However,...

chapter

An integrated GNSS remote sensing instrument and its first GNSSR airborne experiment

Xianyi Wang, Yueqiang Sun, Qifei Du, Dongwei Wang, more

2016 IEEE International Geoscience and Remote Sensing Symposium (IGARSS) > 4827 - 4830

IGARSS 2016 - 2016 IEEE International Geoscience and Remote Sensing Symposium

This paper presents the latest development of NSSC's integrated GNSS remote sensing instrument. This new instrument is flexible designed for a variety of GNSS science needs based on the successful GNOS receiver, but with more functional modules. The goal of this instrument is to be put onboard of future Chinese space-borne platforms to provide precise position and timing information for high-demand...

article

Quantification of the relative role of land-surface processes and large-scale forcing in dynamic downscaling over the Tibetan Plateau

Yanhong Gao, Linhong Xiao, Deliang Chen, Fei Chen, more

Climate Dynamics > 2017 > 48 > 5-6 > 1705-1721

Dynamical downscaling modeling (DDM) is important to understand regional climate change and develop local mitigation strategies, and the accuracy of DDM depends on the physical processes involved in the regional climate model as well as the forcing datasets derived from global models. This study investigates the relative role of the land surface schemes and forcing datasets in the DDM over the Tibet...

chapter

Fireworks Explosion Optimization algorithm for parameter identification of PV model

Qing Zhang, Hongda Liu, Cheng Dai

2016 IEEE 8th International Power Electronics and Motion Control Conference (IPEMC-ECCE Asia) > 1587 - 1591

2016 IEEE 8th International Power Electronics and Motion Control Conference (IPEMC 2016 - ECCE Asia)

Photovoltaic (PV) cell is the energy source of the PV generation systems. Accurate electrical characteristic of PV array is the premise condition of the efficient operating PV systems. PV cells are strongly nonlinear model of multi-parameters, and we use the way of identifying PV mathematical model to get these parameters. The accurately method of PV array model identification has a very important...

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Charakterystyka osuwisk powstałych na hałdach po górnictwie rud żelaza w rejonie częstochowskim

Multivariate decoding methods reveal how speaking two dialects affects executive functions

Auditory spatial attention gradients and cognitive control as a function of vigilance

A strategy to characterize chlorophyll protein interaction in LIL3

Single-trial dynamics explain magnitude sensitive decision making

Solving electromagnetic scattering from complex composite objects with domain decomposition method based on hybrid surface integral equations

Pharmacokinetic Characterization and Dose Selection of a Novel Sumatriptan Nasal Spray Formulation, DFN‐02

Feature-based diagnostic distortion measure for unsupervised self-guided biomedical signal compressors

DDM at Work

Estimation of maximum power point of a double diode model photovoltaic module

A multicenter, open-label, long-term safety and tolerability study of DFN-02, an intranasal spray of sumatriptan 10 mg plus permeation enhancer DDM, for the acute treatment of episodic migraine

Investigation of efficient simulation methods for finite large X-band arrays in HFSS

Rapid and sensitive analysis of N-glycans by MALDI-MS using permanent charge derivatization and methylamidation

Integrated simulation of multi-stage hydraulic fracturing in unconventional reservoirs

A Randomized Trial Comparing the Pharmacokinetics, Safety, and Tolerability of DFN‐02, an Intranasal Sumatriptan Spray Containing a Permeation Enhancer, With Intranasal and Subcutaneous Sumatriptan in Healthy Adults

Coupling of BEM subdomains – BETI applied to collocation BEM with mixed basis functions

Influences of 3D Aircraft Model to ILS Localizer

An integrated GNSS remote sensing instrument and its first GNSSR airborne experiment

Quantification of the relative role of land-surface processes and large-scale forcing in dynamic downscaling over the Tibetan Plateau

Fireworks Explosion Optimization algorithm for parameter identification of PV model

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