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The problem of a spherically symmetric dilatation in a spherical gel, important for understanding the mechanical behavior of hydrogels and biogels (e.g., drug-delivery vehicles, mineralized organic gels), is solved analytically using second-order elasticity theory. The solutions are developed via a perturbation method up to the cubic terms of the strains. Using elastic constants for a gel derived...
Two enzymes, thrombin and transglutaminase, both participate in the formation of fibrin networks and contribute to the mechanical strength of biogels. A theoretical model built from the available kinetic data showed that a competition may take place between the two enzymes for their common substrate, fibrinogen. To evidence this phenomenon experimentally, the concentrations of the reactants were varied...
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