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We explore the potential application of resistive pulse sensing technology for transport time-independent determining the size and surface charge density of individual nanoparticles simultaneously. The translocation of both uncharged and charged nanoparticles through a nanopore was modeled using the finite element simulation. A positive peak appears when a charged, but not uncharged, nanoparticle...
Tunable resistive pulse sensing has been used to measure the zeta potential of two sets of 200 nm diameter polystyrene nanoparticles in 0.1 M KCl electrolyte. Data were analysed using two methods, both of which yield particle-by-particle zeta potential values based on electrophoretic mobility. Five pore specimens were used, and in most cases data clearly indicate that one particle set had a higher...
Lipoprotein particles (LPPs) are biological nanoparticles whose physiological roles are greatly influenced by their sizes. The four major classes of LP are: very low density lipoprotein, intermediate density lipoprotein, low density lipoprotein (LDL) and high density lipoprotein. Since the predominance of small, dense LDLs is associated with increased risk of coronary artery disease (CAD) and diabetes...
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