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Senescence of the organism is a consequence of several molecular (induction of proapoptotic genes expression, DNA damage) and biochemical changes, which gradually leads to the degeneration of some systems and organs. One of the most important features of progressive senescence is also a decreased response of the immunological system (proinflammatory response), which may result in a higher susceptibility...
Curcumin (diferuloylmethane), a yellow poliphenol pigment isolated from rhizome of Curcuma longa, has been used throughout Asia for several thousands of years. Beside giving curry dishes their color, curcumin has been reported as an agent used in the treatment of various disorders. The aim of this study was to determine the effect of chronic curcumin administration on enzymatic and nonenzymatic protective...
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