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Background and objective
Rhinoviruses (RV) replicate in both upper and lower airway epithelial cells. We evaluated the possibility of using nasal epithelial cells (NEC) as surrogate of bronchial epithelial cells (BEC) for RV pathogenesis cell culture studies.
Methods
We used primary paired NEC and BEC cultures established from healthy subjects and compared the replication of RV belonging to the...
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