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Terahertz pulsed imaging (TPI) was used to analyse the diffusion of water into hydroxypropyl methyl cellulose (HPMC) matrices as well as acrylate copolymer matrices in reflection. Using TPI it is possible to monitor the phase changes that occur in the polymer matrix, investigate the growth kinetics of the process as well as follow the water diffusion front as it propagates through the porous polymer...
We present an analysis of terahertz pulsed imaging (TPI) measurements made on pharmaceutical tablets compacted at a range of compression forces. In particular, we investigate the uniformity and local variations in the refractive index on the surface of tablets of different shapes. Through terahertz imaging it has been possible to observe small-scale deviations on tablet surfaces that may have relevance...
A new optical platform for the interrogation of a polymethylmethacrylate (PMMA) multichannel array for chemical and biochemical parameters is described. It consists of a plastic chip formed by two pieces of PMMA properly shaped in order to obtain different microchannels, 500 mum in width and 400 mum in height. A fluorescent sensing layer is immobilized on the internal wall of the microchannel. The...
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