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La pré-éclampsie (PE) est définie comme une hypertension de novo et une protéinurie après 20semaines de gestation chez des femmes normotendues, avec une incidence de 3 à 7 % des grossesses. La physiopathologie de la PE reste imparfaitement comprise et est caractérisée par un modèle en deux étapes : la phase présymptomatique avec défaut d’invasion trophoblastique et défaut de remodelage vasculaire...
Fibrosis is characterized by disproportionate accumulation of collagens and other extracellular matrix substances, resulting in organ dysfunction and failure. In systemic sclerosis, cellular and molecular mechanisms involved in the pathophysiology of fibrosis are highly complex and yet barely understood. Anatomopathological findings showed the coexistence of patchy inflammatory cell infiltration,...
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