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Oxytocin (OT) is considered to be a stress-buffering hormone, dampening the physiologic effects of stress. However, OT can also be anxiogenic. We examined acute and long-lasting effects of social defeat on OT neurons in male and female California mice.We used immunohistochemistry for OT and c-fos cells to examine OT neuron activity immediately after defeat (n = 6–9) and 2 weeks (n = 6–9) and 10 weeks...
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