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BACKGROUND:Reduced melanoma risk has been reported with regular use of nonsteroidal anti‐inflammatory drugs (NSAIDs). However, the ability of NSAIDs to reach melanocytes in vivo and modulate key biomarkers in preneoplastic lesions such as atypical nevi has not been evaluated.
METHODS:This randomized, double‐blind, placebo‐controlled trial of sulindac was conducted in individuals with atypical nevi...
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