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Aurozymes
Aurozyme, a novel nanozyme, effectively treats inflammatory bowel disease (IBD). Composed of gold nanoparticles and glycyrrhizin with a glycol chitosan coating, it scavenges harmful radicals and molecular patterns in colitis. Aurozyme's unique catalase‐like activity converts hydroxyl radicals to water and oxygen, reducing inflammation and promoting tissue repair. It also regulates gut microbiota,...
A therapeutic strategy that could address colitis of multiple etiologies while restoring the dysbiosis of gut microbiota is attractive. Here, Aurozyme, a novel nanomedicine comprised of gold nanoparticles (AuNPs) and glycyrrhizin (GL) with a glycol chitosan coating layer, as a promising approach for colitis, is demonstrated. The unique feature of Aurozyme is the conversion of harmful peroxidase‐like...
Oral antioxidant nanozymes bring great promise for inflammatory bowel disease (IBD) treatment. To efficiently eliminate reactive oxygen species (ROS), various metal‐based nanozymes have been developed for the treatment of IBD but their practical applications are seriously impaired by unstable ROS‐eliminating properties and potential metal ion leakage in the digestive tract. Here, the authors for the...
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