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— A comparative study of morphogenesis and synaptogenesis of the sensorimotor cortex and changes in motor behavior during early ontogenesis (Р5, Р14) of rats with normal development and rats subjected to prenatal hypoxia at Е14 (7% O2, 3 h) has been performed. The rats subjected to prenatal hypoxia exhibited delayed maturation of neural elements of the sensorimotor cortex in the first 2 weeks of postnatal...
α-Synuclein (α-syn) is a presynaptic protein present at most nerve terminals, but its function remains largely unknown. The familial forms of Parkinson’s disease associated with multiplications of the α-syn gene locus indicate that overabundance of this protein might have a detrimental effect on dopaminergic transmission. To investigate this hypothesis, we use adeno-associated viral (AAV) vectors...
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