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Sono/Photoinduced Therapy
In article number 2104473, Zhiyong Qian and co‐workers describe the design, preparation, and evaluation of newly constructed self‐assembled nanoparticles (CS‐ss‐IR806, CSR NPs) with a redox/hyaluronidase‐responsive and mitochondria‐targeting capability to treat the early‐stage and localized prostate cancer via a photo‐/sono‐induced focal therapeutic strategy.
Focal therapy, or partial gland ablation, represents the middle ground between active surveillance and definitive treatment strategies against localized prostate cancer (PCa), among which the ultrasound‐ and light‐mediated focal therapies are quite promising. Herein, for the first time in the literature, a novel polysaccharide‐based nanoprodrug is fabricated for synergistic sonodynamic therapy and...
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