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Interdigitated electrode based electrical biosensors are prominent in biosensor field. The large number of finger electrodes as comb structure gain high sensitivity through electrical measurements. Listeria monocytogenes is a serious food borne pathogen based bacterium that can cause dangerous disease to human, some infection may result in death. In here, biosensor was prepared from 1μm gap Aluminum...
This research studies the detection of Human Papillomavirus (HPV) by using a colorimetric method for visualizing biotin-labelled DNA probes hybridized to DNA HPV on silicon dioxide (SiO2). In this study, SiO2 was used as substrate to check hybridization between HPV DNA probe and HPV DNA target. HPV is a virus that spreading by sexually transmitted that infected to human especially woman. High-risk...
We present the fabrication and electrical characterization of polysilicon and their properties with application in biomolecule sensors for DNA detection. Conventional photolithography technique was used to fabricate the DNA detection structure for two different wafer substrate i.e. N- and P-type. The fabrication processes involve of deposition, etching and oxidation to achieve the final structure...
This paper presents the use of direct capacitance measurements for label free hybridization detection of ssDNA immobilized directly on a gold interdigitated array of microelectrodes (IDAM). Thiol modified 18 bases long Poly-dT ssDNA molecules were immobilized on the Au IDAM surface without the use of any isolative self assembled monolayer (SAM). Afterwards a Poly-dA ssDNA solution was deposited on...
Fabrication and electrical characterization of 5-nm polysilicon gaps and their properties are discussed with their application in electrochemical sensors and biomolecule detection. To understand the relationship between the biosensor and nanotechnology we have carried out the fabrication and characterization of nanogap structures for DNA detection. In this paper, 2 mask designs are used. The first...
Gold-coated microcantilevers were used to develop sensitive micromechanical biosensor for detecting mismatch mutations in DNA hybrids. The selective 5'-end immobilization of 25-mer single-stranded (ss) DNA probes to a gold-coated cantilever surface and the specific hybridization of ssDNA targets to the immobilized probe were performed by the direct electric field control. The controlled electric fields...
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