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Solvent conditions are unexpectedly sufficient to drastically and reversibly slow down cells. In vitro on the molecular level, protein–solvent interactions drastically change in the presence of heavy water (D2O) and its stronger hydrogen bonds. Adding D2O to the cell medium of living cells increases the molecular intracellular viscosity. While cell morphology and phenotype remain unchanged, cellular...
In article number 2101840, Jörg Schnauß and co‐workers show that heavy water (D2O) reversibly slows down cells, retards cell invasion, and drastically impacts cell mechanics, possibly prolonging storage times for biological materials. The cellular dynamics, which transform into slow motion, can be captured via the time‐temperature superposition principle, where temperature is replaced by D2O. Induced...
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