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ObjectiveTo compare manual and automated preoperative and postoperative hippocampal volume measurements in patients with intractable epilepsy.
MethodsWe studied 34 patients referred to the Clinical Epilepsy Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) for evaluation of intractable epilepsy and 21 normal volunteers who received 1.5 or...
Hippocampus segmentation is a key step in the evaluation of mesial Temporal Lobe Epilepsy (mTLE) by MR images. Several automated segmentation methods have been introduced for medical image segmentation. Because of multiple edges, missing boundaries, and shape changing along its longitudinal axis, manual outlining still remains the benchmark for hippocampus segmentation, which however, is impractical...
Brain structural volumes can be used for automatically classifying subjects into categories like controls and patients. We aimed to automatically separate patients with temporal lobe epilepsy (TLE) with and without hippocampal atrophy on MRI, pTLE and nTLE, from controls, and determine the epileptogenic side. In the proposed framework 83 brain structure volumes are identified using multi-atlas segmentation...
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