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For decades neuroreceptor research has focused on the development of NMDA glycine-site antagonists, after Johnson and Ascher found out in 1987 about the co-agonistic character of this achiral amino acid at the NMDA receptor. Contrary to the inhibitory glycine receptor (glycine A ) the glycine binding site on the NMDA receptor (glycine B ) is strychnine-insensitive. A great diversity...
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