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Résumé: Malgré une incidence croissante du cancer du sein dans la population âgée, les données spécifiques prospectives concernant sa prise en charge après 70 ans, tout particulièrement pour les indications de chimiothérapie adjuvante, sont rares dans la littérature, gênant l’application de recommandations standards établies essentiellement chez les sujets plus jeunes. La plupart des données dérivent...
Résumé: Chez les femmes non ménopausées la survie des cancers du sein exprimant des récepteurs d’estradiol et ou de progestérone est améliorée significativement par différentes modalités d’hormonothérapie adjuvante: la suppression de la fonction ovarienne quand il n’y a pas de chimiothérapie, la suppression de la fonction ovarienne associée au tamoxifène et le tamoxifène seul qu’il y ait ou non une...
The role of chemotherapy in the treatment of operable soft tissue sarcomas is still debatable. In high-grade tumors, randomized trials using adjuvant chemotherapy have resulted in controversial results. A recent meta-analysis showed a higher median disease-free survival in groups with chemotherapy compared to controls. Doxorubicin, ifosfamide and dacarbazine are the majors drugs. Their combination...
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