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Regeneration of the immune system after hematopoietic stem cell transplantation (HSCT) is a slow process. We attempted to identify problems in the recovery of the immune system by examining expressions of early event cell cycle proteins Myc, Jun, and Fos, as well as DNA binding of Myc, activating protein 1 (AP-1), and CD4 cell activation values, in phytohemagglutinin-activated T lymphocytes taken...
Regeneration of the immune system after hematopoietic stem cell transplantation (HSCT) is a slow process. Early cell cycle proto-oncogenes are key players in the first events of the proliferative process of T-cell immune response. To identify the causes of the prolonged immuno-suppression after transplantation we evaluated the expression of early T-cell cycle genes c-myc, c-jun and c-fos in peripheral...
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