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Gold - poly(dimethylsiloxane) (Au - PDMS) nanocomposite freestanding films were prepared and used to study the binding of Human Serum Albumin (HSA) to polyclonal anti-HSA. A new method of synthesis was developed for sensing application when most of the gold nanoparticles have to be localized in the surface layer. The localized surface plasmon resonance band in gold nanoparticles is used to monitor...
Ultrasound imaging is a relatively low cost, portable and non-invasive medical imaging modality for the diagnosis of a wide spectrum of diseases. Molecular imaging of diseases provide valuable information for improved disease diagnosis and management and has been developed to integrate into various medical imaging platform. However, no molecular probes has been developed for ultrasound imaging to...
We describe the design of a 4times4 active sensor array for multiplexed electrochemical biomolecular detection in a 0.25-mum-CMOS process. Integrated potentiostats sense the current flowing through the on-chip Au electrodes that result from reactions occurring at the chip surface. Preliminary experimental results include cyclic voltammetry of several redox species and application to DNA probe coverage...
Conducting polymer can modify device surface properties and incorporate biomolecules for immobilization by electropolymerization at the same time. We investigated a method for surface modification by electrochemically deposited polypyrrole onto surface of bio-MEMS micro device. We reported the effects of the numbers of CV cycle on the deposited film thickness and roughness in this paper. Furthermore,...
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