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Finding the longest cycle is a novel concept in biochemical feedback loop analysis in systems biology. Biochemical networks are often represented as directed graphs in which vertices represent chemical compounds and edges represent chemical reactions between compounds. Therefore, a biochemical longest feedback loop can be formulated as the longest cycle in a directed graph. Because finding the longest...
We introduce a graph-based relational learning approach using graph-rewriting rules for temporal and structural analysis of biological networks changing over time. The analysis of dynamic biological networks is necessary to understand life at the system-level, because biological networks continuously change their structures and properties, while an organism performs various biological activities....
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