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Recent advances in the fabrication of microfluidic platforms initiated during the late 90s have facilitated the realisation of micro total analysis systems. The integration of miniaturised fluidic handling and delivery systems with chemical and biochemical sensors provide applied scientists with powerful tools for in-field measurements away from central laboratories. Amongst the various classes of...
1H NMR-based metabonomic method was used to investigate the biochemical variability in serum from rats treated by nephrotoxins. The toxic effect of the model toxins, sodium chromate (Na2CrO4, 20 mg/kg body mass), 2-bromoethanamine hydrobromide (BEA, 250 mg/kg body mass) and mercury II chloride (HgCl2, 1 mg/kg body mass), was evaluated by 1H NMR spectroscopy accompanied by principal components analysis...
Atherosclerosis (ACS) has set off the innovation of molecular markers measured in plasma or serum, and used for the identification of individuals at high risk of Coronary Heart Disease (CHD). In an attempt to improve cardiovascular risk prediction, considerable interest is focused on inflammatory biomarkers including Interleukin (IL)-6, Phospholamban (PLB), Myocyte enhancer factor 2A (MEF2A), and...
Atherosclerosis (ACS) has set off the innovation of molecular markers measured in plasma or serum, and used for the identification of individuals at high risk of Coronary Heart Disease (CHD). In an attempt to improve cardiovascular risk prediction, considerable interest is focused on inflammatory biomarkers including Interleukin (IL)-6, Phospholamban (PLB), Myocyte enhancer factor 2A (MEF2A), and...
We present a three parametric model using Raman and fluorescence spectroscopy for detection and analysis of esophagus dysphasia and esophagus cancer. The model was set up from more than 200 samples. And 40 samples were used to test this algorithm of the model prospectively. The serum spectra were excited by laser of the wavelength 488.0 nm and 514.5 nm. The apparent differences of auto-fluorescence...
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