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Objective: To study the effect of IFN-alpha2b on HBVDNA and inducement to CD25 of the patients with chronic hepatitis B. Methods: All of patients were divided into two groups and treated by IFN-alpha2b, routine medicine, respectively. The levels of HBV-DNA in PBMC and serum, and CD25 and CD25 mRNA, and anti-IFN-IgG were respectively detected by real-time PCR, biotin-streptavidin (BSA) and ELISA. Results:...
Systemic chemotherapy is widely used for treatment of metastatic colorectal cancer (CRC). However, many CRC patients show poor response to chemotherapy and suffered from toxicities. Thus, prediction of chemotherapy response is very important in effective therapy. In the present study, we investigated whether chemotherapy response of CRC can be predicted by nano-assisted laser desorption/ionization...
Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI or SELDI-TOF MS) with protein arrays has facilitated the discovery of disease-specific protein profiles in serum. As array technologies in bioinformatics and proteomics multiply the quantity of data being generated, more automated hardware and computational methods will become necessary in order to keep up. Robot...
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