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The ideal graft for use in anterior cruciate ligament reconstruction should have structural and biomechanical properties similar to those of the native ligament, permit secure fixation and rapid biologic incorporation, and limit donor site morbidity. Many options have been clinically successful, but the ideal, graft remains controversial. Graft choice depends on surgeon experience and preference,...
The purpose of this study is to assess platelet and fibrin targeted ultrasound contrast microbubbles ability to adhere to fresh platelet and platelet poor clots in vitro with the assistance of radiation force. Whole blood from healthy volunteers (25 ml) was collected and centrifuged at 1100 rpm for 15 min to separate platelet-rich plasma (PRP), which was separated and centrifuged (3000 rpm, 5 min)...
Platelet-rich plasma (PRP) has been gaining increasing popularity in orthopedics and oral and maxillofacial surgery because of its potential efficacy in enhancing bone regeneration. To maximally augment bone healing using PRP and to control the bioavailability of the relevant growth factors, we have designed an alginate hydrogel-based PRP-delivery system. The bioactivity of the growth factors released...
Platelet-rich plasma (PRP) has been gaining increasing popularity in orthopedics and oral and maxillofacial surgery because of its potential efficacy in enhancing bone regeneration. To maximally augment bone healing using PRP and to control the bioavailability of the relevant growth factors, we have designed an alginate hydrogel-based PRP-delivery system. The bioactivity of the growth factors released...
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