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In this study we investigated the influence of Photofrin-based photodynamic therapy (PDT) on the migration of two human glioma cell lines in vitro. U87 and U25ln tumour cells were treated with Photofrin at various doses and subjected to a fixed optical (632nm) dose of 100mJ/cm2. Photofrin cytotoxicity was determined using MTT and colony forming assays. Using a matrigel artificial basement membrane...
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