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Pancreatic Adenocarcinoma is the most common pancreatic cancer. This occurs in 90% of all human pancreatic cancers. It is the most devastating disease, with overall 5-year survival rate of only 3–5%. In 2014, it was estimated that in the US, 46,000 new cases will occur with more than 40,000 deaths. This indicates that the current standard of cure is inadequate. Typically they are diagnosed at the...
Measurement of objective response to chemotherapy using imaging modalities is sometimes difficult in pancreatic cancer (PC). We aimed to verify whether monitoring of serum tumor markers (TMs), namely carcinoembryonic antigen, CA19-9, DUPAN-2, SPan-1, can facilitate earlier confirmation of treatment failure.Monitoring of serum TMs and computed tomography were performed every 4 weeks until progression...
Über 90% der Pankreaskarzinome sind duktale Adenokarzinome des exokrinen Pankreas. An der hohen Sterblichkeit hat sich im Lauf der letzten Jahre wenig geändert. Typische Erstsymptome treten erst spät im Verlauf der Erkrankung auf und bestehen in dumpfen Oberbauchschmerzen mit Ausstrahlung in den Rücken, Inappetenz mit Gewichtsverlust oder einem Verschlussikterus. Die meisten Betroffenen erkranken...
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