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While antitumor immunological responses have been mainly associated with necrosis, immune responses associated with apoptosis have been suggested recently. In this study, the relationship between cell death and its interaction with macrophage were studied using Photofrin-PDT induced necrosis and apoptosis.
Cadmium (Cd) and Copper (Cu) are common transition metals found in the environment. The toxic effects of Cd on human health have received considerable concerns. Cu is the trace essential element, however, excess amounts of copper causes toxic effects to life. To have a better understand of the impacts of heavy metals exposure on human beings as well as other animals, many bioassay systems have been...
AIM: In the present study, murine A549 Lung cancer cells were provided Lung cancer with different thermal dose invitro and invivo, thereafter we investigated the apoptosis, necrosis rates, and intratumoral microvessel density (MVD) to determine that microvessel damage plays an important role in the tumoricidal effect of Lung cancer. Methods: A549 Lung cancer cells were inoculated in the right hind...
Induction of apoptosis, or programmed cell death, is an important factor in cancer therapy as cancer cells frequently have acquired the ability to avoid apoptosis and continue to multiply in an unregulated manner; thereby becoming resistant to traditional chemotherapeutic drugs. Nonthermal atmospheric plasma discharge may provide a novel approach to induction of apoptosis in cancer cells. The purpose...
Cell growth and cell division are fundamental aspects of cell behavior in all organisms. Recent insights from many model organisms have shed light on the molecular mechanisms that control cell growth and cell division. A significant body of evidence has now been accumulated, showing a direct link between deregulation of components of cell cycle machinery and cancer. Cancer can be described as a genetic...
Summary form only given. Over the last several years pulse power technology has developed into a novel and innovative time domain nanotechnology as a new modality to treat cancer. The technology treats cancer in the absence of drugs by generating non-ionizing radiation with nanosecond pulsed electric fields (nsPEFs or nanopulses) that are high in power (gigawatts) and low in energy (millijoules)....
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