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Caveolin‐1 is a main structural component of caveolae and essential for the invagination of caveolae by forming a hairpin‐shaped structure in the membrane‐inserting domain (residues, 102–122). In this article, we determined the tertiary structures of the peptides comprising residues 93–126 and 101–126 of caveolin‐1 in 1,1,1,3,3,3‐hexafluoro‐2‐propanol (HFIP) aqueous solution and sodium dodecyl sulfate...
Des-acyl-ghrelin is a 28 amino acid peptide secreted by both human and rat stomach. Together with ghrelin and obestatin, it is obtained by post-translational modification of a 117 aminoacid prepropeptide mainly expressed in distinct endocrine cell type in the stomach. Although its receptor has not been unambiguously identified so far, des-acyl-ghrelin is considered one of the strongest antagonists...
Solid-state NMR and CD spectroscopy were used to study the effect of antimicrobial peptides (aurein 1.2, citropin 1.1, maculatin 1.1 and caerin 1.1) from Australian tree frogs on phospholipid membranes. 31 P NMR results revealed some effect on the phospholipid headgroups when the peptides interact with DMPC/DHPC (dimyristoylphosphatidylcholine/dihexanoylphosphatidylcholine) bicelles and...
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