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Nicht kodierende regulatorische Ribonukleinsäuren (RNAs), wie z. B. microRNAs, lange nicht kodierende RNAs und zirkuläre RNAs, können die Genexpression von Entzündungsmediatoren und somit den Verlauf und das Fortschreiten einer chronisch entzündlichen Erkrankung beeinflussen. Neuere Studien unter Verwendung von Antisense-Oligonukleotiden zeigen, dass sich nicht kodierende regulatorische RNAs als neuartige...
Objective The aim of this study was to explore whether polymorphisms in miR-146a, miR-499 and IRAK1 are associated with susceptibility to inflammatory arthritis. Methods Manual searches performed in the MEDLINE and EMBASE databases were used to identify published articles in which the roles of microRNA (miRNA) and IRAK1 polymorphisms in inflammatory arthritis were determined. A meta-analysis was...
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