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Antimony trichloride absorbed on silica gel (SbCl3/SiO2) efficiently catalyses the four-component cyclocondensation of 1,2-diketone, aldehyde, ammonium acetate, and primary amine under solvent-free conditions to afford the corresponding tetrasubstituted imidazoles in high yields. The main merit of this study is introducing a novel catalyst to successful synthesis of a wide range of 1,2,4,5-tetrasubstituted...
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