The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Cardiac Resynchronization Therapy (CRT) has emerged as an important therapy to improve pump function in heart failure patients with left bundle branch block (LBBB). Using a multi-scale modeling approach, we investigated the effect of mechano-electrical feedback (MEF) during LBBB and CRT on cardiac function and dispersion of repolarization. Our model describes cellular electrophysiology and calcium...
Comprehensive understanding of hemodynamics remains a challenge even for expert cardiologists, partially due to a lack of an appropriate macroscopic model. We attempted to amend three major problems of Guyton's conceptual model (unknown left atrial pressure, unilateral heart damage, blood redistribution) and developed a comprehensive macroscopic model of hemodynamics that provides quantitative information...
Here we describe new computational models of cardiac electromechanics starting from the cellular scale and building to the tissue, organ and system scales. We summarize application to human genetic diseases (LQT1 and LQT3) and to modeling of congestive heart failure.
Ventricular intramyocardial electrograms are recorded with electrodes directly from the heart either in intraventricular or epimyocardial position and may be acquired either from the spontaneously beating or from the paced heart. The morphology of these signals differs significantly from that of body surface ECG recordings. Although the morphology shows general characteristics, it additionally depends...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.