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This study examines the dynamic linkages between the major equity markets of the world (USA, Japan and Britain) and the emerging markets of South-East Europe (Croatia, Slovenia and Hungary). In particular, we discuss possible differences between their interdependences during the period of the dot-com speculative bubble, as well as during the period of the existing financial crisis caused by deflation...
Cellular signaling circuitry in eukaryotes can be studied by analyzing the regulation of protein phosphorylation and its impact on downstream mechanisms leading to a phenotype. A primary role of phosphorylation is to act as a switch to turn “on” or “off” a protein activity or a cellular pathway. Specifically, protein phosphorylation is a major leit motif for transducing molecular signals inside the...
Evaluation of gene regulatory network (GRN) discovery methods relies heavily on synthetic time series. However, synthetic data generated by traditional method deviate a lot from real data, making such evaluation questionable. Guiding by decaying sinusoids, we propose a new method that generates synthetic data resembling human (HeLa) cell-cycle gene expression data. Using the new synthetic data, a...
Exploring directed influence relationships at different temporal and spatial scales is an important issue in time-series research. This paper develops a method for testing the directed interactions of multivariable time-series with a vector autoregressive (VAR) model. The calculation of Granger causality between the reference time-series and the other time-series is not rely on a priori specification...
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