The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
This paper reports the analysis of drug effects on single breast cancer cells using the droplet-microfluidic devices for the first time. Hundreds of droplets can be generated in less than 5 minutes. Each droplet serves as a nanoliter-volume titer plate. About 50% of the droplets contain a human breast cancer cell MDA-MB-231 and Cytochalasin D drug solution. The drug effects on each cell are monitored...
In this paper, author will provide a broad review of breast cancer research conducted at the University of Pennsylvania and collaborative work with other institution. Our group led by Dr. Arjun G. Yodh has been actively exploring functional and physiological information available via the diffuse optical technique and investigate its use in the area of in vivo breast cancer detection, diagnosis, and...
Following the uptake kinetics of a monoclonal antibody cancer therapy in vivo is addressed in this study via the use of a surface probe to assay a fluorescent label attached to the antibody. Female NCr-nu athymic mice were implanted with cells from a human breast cancer MCF7HER2 line that over expresses clinically relevant levels of the HER2/neu protein. Herceptin (trastuzumab) and a negative control...
Two-photon flow cytometry is demonstrated for simultaneous monitoring of two separate cell lines in a mouse. The technique is used to study the roles of proteins in regulating the trafficking of circulating metastatic cancer cells.
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.