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Drugs circulation channels are not only related to the drug industry development, but also the human health and safety, therefore, the implementation of government supervision on drug circulation channel is one of the key content of the social and economic regulation. This paper established a basic model of drug circulation channel of government supervision, and tried to seek and explore a more effective...
Patients in intensive care units are often prescribed a combination of sedative and analgesic to manage anxiety and pain relief. Proper sedation management is crucial to patient recovery but few intensive care units routinely employ strategies that tailor drug delivery to ongoing patient needs. The Infuse-Rite has been developed to automate a protocol that eliminates the possibility of excessive sedation...
QT interval prolongation is one of the most common causes of delays and non-approvals in drug development due to the qualitative relationship between this interval and Torsade de Pointes (TdP) arrhythmia. However, not all drugs that prolong the QT interval to the same extent carry the same risk for TdP. Other indications, such as abnormal T-wave morphology, may play a role in differentiating between...
Phenylephrine is a drug used at BC Women's Hospital, Vancouver BC to treat maternal hypotension induced by spinal anesthesia. Its dosage is mainly determined in a heuristic manner by the anesthetist's experience. Since an overdose of phenylephrine can result in bradycardia and hypertension, anesthesiologists are in need of a systematic method to calculate the correct dose. This problem is formulated...
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