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The small number of patients enrolled in clinical trials to test new drugs and the relatively short trial durations make it paramount to monitor drugs' effectiveness and risks after they are approved by the regulatory agency. A thorough evaluation of a drug's effectiveness, side effects, and social and economic influences can prevent serious health damage to the public and shed light on new drug discovery...
Millions of patients are affected by adverse drug reactions (ADRs) every year. It represents a substantial burden on healthcare resources. Pharmacovigilance using text and data analytics has drawn substantial attention in the recent years. These techniques are mainly extracting the associations between drugs and ADRs using data sources such as spontaneous reporting systems, electronic health records,...
Drug-drug interactions (DDIs) are a serious drug safety problem for health consumers and how to detect such interactions effectively and efficiently has been of great medical significance. Currently, methods proposed to detect DDIs are mainly based on data sources such as clinical trial data, spontaneous reporting systems, electronic medical records, and chemical/pharmacological databases. However,...
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