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Experimental methods such as high-throughput screening have widely used for discovery of the new drug targets. We employed an idea that disease-related proteins tend to be work as an important factor for architecture of the disease network in this study. To determine new drug target proteins, we proposed a new methodology that analyzes the human disease network by using informational technology. We...
Alzheimer's disease (AD) is characterized by Abeta plaques, amyloid angiopathy, and NFTs. The ongoing challenge is to integrate present resources as to discover the unkown mechanism and propose possible treatment targets. In this paper, we attempt to find the cause and treatment of AD with computational approach by making use of KEGG,GeneCards, Brenda, DrugBank and STRING.
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